Extraembryonic trophoblast lineages constitute the placenta, and are essential for individual development. In human early embryo development, these cells can be generated from totipotent blastomeres.

An innovative organoid model mirrors the pancreas' complexity, generating all three key cell types to explore development and ...

In a breakthrough for the advanced study of gut health, scientists have developed a 3D microscopic version of the human intestines condensed into a small chip about half the size of a five-cent coin.

Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner. Targeting vimentin and/or the long ...

Graft-versus-host disease (GVHD) is a common and severe complication that occurs after stem cell transplantation, where the ...

The Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures has added the syphilis pathogen to its ...

report a method for multiplexing isogenic iPSCs for single-cell RNA-seq. With it, they created an atlas of in vitro differentiation ... differentiation of human dental pulp stem cells by sponging ...

In summary, enalapril significantly mitigated multiple pathological markers associated with aging, including lipid droplets, amyloid, glycogen deposition, and fibrosis, in the brain, kidneys, liver, ...

Humans evolved late in Earth history. While this timing inspired the conclusion that humanlike life is a cosmic improbability ...

Traditional static 2D culture systems, where cells are grown as a monolayer on flat surfaces, fall short of capturing the complexity and physiological ...