Accumulation of fat molecules is detrimental to the cell. Researchers from the Yong Loo Lin School of Medicine, National ...

Given the success of the previous Research Topic 'Exploring Small Molecule Inhibitors in Cardiovascular and Cerebrovascular Diseases', we are pleased to ...

Pharmaceutical ads are difficult to avoid in American television programming and a growing number of them promote a class of ...

Intercellular adhesion can be mediated by adherens junctions, tight junctions and desmosomes, whereas cells can interact with extracellular matrix molecules ... outside-in signaling, which ...

With the strong associations established in epidemiologic studies and a dearth of evidence on the actual mechanisms by which ...

A type of aggressive, treatment-resistant brain tumor has a distinct population of immune cells that support its growth, ...

Get Instant Summarized Text (Gist) Molecules have been successfully trapped to perform quantum operations, marking a significant advancement in quantum computing. By using ultra-cold polar ...

The study is among the first to show that the rotavirus protein NSP4 is both necessary and sufficient for multiple aspects of rotavirus infection by disrupting calcium signaling not only within ...

Studies by Jeffrey Klomp et al. 6 and Jennifer Klomp et al. 7 refine our understanding of the signaling effects of oncogenic KRAS. The studies suggest that mutant KRAS signals predominantly ...

The primary node molecules in the cell signaling network in cancer tissues are maladjusted and mutated in comparison to normal tissues, which promotes the occurrence and progression of cancer.

Kirsten rat sarcoma (KRAS) is a potent oncogenic driver that results in the downstream hyperactivation of MAPK signaling while simultaneously increasing replication stress (RS) and accumulation of DNA ...