Functional subpopulations of β-cells emerge to control pulsative insulin secretion in the pancreatic islets of mice through calcium oscillations.

The researchers investigated the impact of intermittent fasting on the beta cells. In the pancreas of mature mice, no negative effects on the beta cells were observed (here stained green).

In this type of diabetes, the immune system specifically destroys insulin-secreting beta cells in the pancreatic islets — the body's own immune system attacks its own cells (a form of autoimmune ...

The distinct population of endothelial cells that line blood vessels in the insulin-producing "islets" of the human pancreas ...

Our perspective about glucose toxicity as it pertains to the pancreatic ß-cell is that the characteristic decreases in insulin synthesis and secretion are caused by decreased insulin gene expression.

Several studies have shown that insulin-producing pancreatic β-cells of patients with diabetes have abnormal mitochondria and are unable to generate energy. Yet, these studies were unable to explain ...