In summary, enalapril significantly mitigated multiple pathological markers associated with aging, including lipid droplets, amyloid, glycogen deposition, and fibrosis, in the brain, kidneys, liver, ...

The first-in-class therapy – a targeted factor B inhibitor – was able to ... iptacopan showed a 60% of greater reduction in lactate dehydrogenase (LDH) levels, a biomarker for haemolysis ...

Specifically, ABP 959 was as effective as Soliris at controlling intravascular haemolysis, one of the hallmarks of PNH, based on its effects on lactate dehydrogenase (LDH) levels. The safety and ...

In the Tennessee Classification System diagnostic criteria for HELLP are haemolysis with increased LDH (> 600 U/L), AST (≥ 70 U/L), and platelets < 100·10 9 /L. The Mississippi Triple-class ...

Here the authors show that this decrease in IFN-I production and related pDC functions may be attributed to suppressed oxidative and glycolytic metabolism of pDCs, with lactate dehydrogenase B ...

Anhui Provincial Key Laboratory of Tumor Evolution and Intelligent Diagnosis and Treatment, Bengbu Medical University, Bengbu, Anhui 233030, China Clinical Testing and Diagnose Experimental Center, ...

Total cell protein was harvested on ice with radioimmunoprecipitation assay lysis buffer (1×Tris-buffer, 1% Nonidet P40, 0.5% sodium deoxycholate and 0.1% sodium dodecylsulfate) in the presence of ...

1 Department of Emergency Medicine, University Medical Center Groningen, Groningen, The Netherlands 2 Department of Intensive Care, University Medical Center Groningen, Groningen, The Netherlands ...