A ligand is an ion or small molecule that binds to a metal atom (in chemistry) or to a biomolecule (in biochemistry) to form a complex, such as the iron-cyanide coordination complex Prussian blue ...

The ability to alter proteins to refine control over binding affinity and specificity can create tailored therapeutics with reduced side effects, highly sensitive diagnostic tools, efficient ...

dynamics and ligand binding via unnatural amino acid incorporation. At Wilkes University, Henkels will be teaching general chemistry and biochemistry lecture and laboratory courses, as well as ...

The key to this is the modification of the original ligand with a reactive "handle" that allows it to react with a nucleobase at the RNA binding site. This was first demonstrated in vitro and in ...