but can also enter the cycle through pyruvate carboxylase. Because islets lack PEPCK activity, the pyvuate/malate or pyvuate/citrate cycling pathways shown could represent important pathways for ...

The pyruvate formed is reduced by NADH in a reaction catalyzed ... L-aspartate and 2-oxoglutarate to yield oxaloacetate and L-glutamate. In the presence of malate dehydrogenase, oxaloacetate reacts ...

A Prescription Drug User Fee Act target date of May 27, 2025 has been assigned to the application. The Food and Drug Administration (FDA) has accepted for Priority Review the New Drug Application ...

There are multiple types of magnesium, some of which may be better for treating certain symptoms and conditions than others. Examples include magnesium citrate and magnesium glycinate. They may ...

Hyperpolarized [1-13 C] pyruvate experiments revealed distinct metabolic profiles for the two cell types, highlighting the bioreactor’s ability to discern metabolic profiles among samples. Our results ...

Plant cellular agriculture aims to disrupt the way plant derived products are produced. Plant cell cultures are typically grown with sucrose as the primary carbon and energy source, but alternative ...

As critical executors regulating many cellular operations, proteins determine whether living activities can be performed in an orderly and efficient manner. Precursor proteins are inert and must be ...

2023 Apr;29(3):862-872. doi:10.1111/odi.14116 Burnett CL, Bergfeld WF, Belsito DV, et al. Amended safety assessment of malic acid and sodium malate as used in cosmetics. Int J Toxicol.

Department of Biochemistry and Synthetic Metabolism, Max Planck Institute for Terrestrial Microbiology, 35043 Marburg, Germany Center for Synthetic Microbiology (SYNMIKRO), 35043 Marburg, Germany ...