The table below is a review of notable updates that occurred in January 2025 for investigational products in development.

The US Food and Drug Administration (FDA) has approved SpringWorks Therapeutics’ Gomekli (mirdametinib) to treat ...

Olive oil bioactives, including MUFAs, polyphenols, and triterpenoids, modulate gene expression linked to insulin sensitivity ...

Mitogen-activated protein kinases (MAPKs) in tomato plants have crucial functions of mediating responses to environmental cues, internal signals, defense mechanisms, cellular processes, and plant ...

Here the authors developed techniques to map bioelectrical excitations in the ... biosensor allows real-time visualization of PKN kinase activity, revealing sustained activity at the plasma ...

This important study demonstrates the potential of synthetic gene circuits to detect and target aberrant RAS activity in cancer cell lines. The circuit design is novel and the evidence supporting the ...

The management of Leishmania donova ni (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment ...

Kinases are enzymes that catalyze the addition of a phosphate group (PO43−) to substrates, usually proteins. The phosphate generally comes from adenosine triphosphate (ATP). Kinases and ...

Lindsey DeSoto, RD, is a nutrition writer, medical reviewer, and registered dietitian who helps clients improve their diet for health-related reasons. Her writing covers a variety of topics ...

Once confined to sportsmen and women, high-protein diets are now commonplace – with Paleo, Atkins, Zone and Dukan advocating that people eat large quantities of fish, meat, eggs, nuts and cheese ...

After hours: February 7 at 4:20:01 p.m. EST ...

Feb. 6, 2025 — Despite new medication, cystic fibrosis often leads to permanent lung damage. Researchers have discovered that the disease causes changes in the immune system early in life ...