A thermal stability-based proteomic analysis identifies cytoplasmic PEBP1 as a mediator of mitochondrial dysfunction-induced stress response, highlighting its potential role in cellular adaptation ...

This “bi-kinase module” sensitises the NADPH oxidase to calcium and enables synergistic activation of this enzyme, which then produces more reactive oxygen species. One of the two calcium-dependent ...

Panel B describes the refined model of KRAS activation informed by the ... GEF guanine exchange factor, MEK mitogen-activated protein kinase kinase, MT mutant, Pi inorganic phosphate, P13K phospho ...