A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular ...

Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase first identified in a chromosomal translocation associated with some anaplastic large cell lymphomas (ALCL), a subset of T-cell non ...

Mitogen-activated protein kinases (MAPKs) in tomato plants have crucial ... Schematic representation of the MAPK cascade. A signal transduction cascade navigates the signal from MAPKKK to MAPK by ...

Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, 12850 East Montview Boulevard, Aurora, Colorado 80045, ...

NOTE. P < .00357 represents statistical significance after the Bonferroni correction. Abbreviations: MAPK, mitogen-activated protein kinase; NA, unable to be calculated; NR, not reached; OS, overall ...

However, the clinical efficacy of mitogen-activated protein kinase (MAPK) pathway inhibitors (MAPKi) for MAP2K1-mutant tumors is not well defined. We sought to characterize the genomic and clinical ...

Sunny with a high of 28 °F (-2.2 °C). Winds NE at 6 to 7 mph (9.7 to 11.3 kph). Night - Clear. Winds from NE to ENE at 5 to 6 mph (8 to 9.7 kph). The overnight low will be -3 °F (-19.4 °C ...