Over 1,000 genes may serve as possible treatment targets for individuals with kidney disease, according to a new study. By creating the most complete and detailed genetic 'map' of kidney function to ...

Researchers determine a complex immune infiltrate pattern based on a newly constructed immune map developed using pancreatic ...

This important study provides new evidence on the role of norepinephrine (NE) release in the hippocampus in response to environmental transitions (event boundaries), providing a potential link between ...

In cancer-associated cachexia, elevated TNF-α and IL-6 exacerbate muscle and fat loss by regulating multiple metabolic signaling pathways, which could be ameliorated by Z526's suppression of NF-κB ...

A thermal stability-based proteomic analysis identifies cytoplasmic PEBP1 as a mediator of mitochondrial dysfunction-induced stress response, highlighting its potential role in cellular adaptation ...

1Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, La Jolla, California.

Want to apply for Canada PR? The country is set to introduce four new permanent residency (PR) pathways in 2025, even as the government plans to reduce its PR targets from 485,000 to 465,000, ...

The studies suggest that mutant KRAS signals predominantly through the rapidly accelerating fibrosarcoma (RAF) effector pathway ... MEK mitogen-activated protein kinase kinase, MT mutant, Pi ...

Because targeting a single signaling pathway often triggers compensatory defensive mechanisms in cancer cells, the researchers believed that the use of several kinase inhibitors that target ...