A joint research team from the LKS Faculty of Medicine (HKUMed) and the Faculty of Science at the University of Hong Kong has uncovered an unexpected interaction between chemotherapeutic agents and a ...

A joint research team from the LKS Faculty of Medicine (HKUMed) and the Faculty of Science at the University of Hong Kong has uncovered an unexpected interaction between chemotherapeutic agents and a ...

Mitosis orchestrates eukaryotic cell division, maintaining genetic fidelity and playing a key role in development, tissue homeostasis, and cancer progression.

Microtubules are cylindrical polymers composed ... formation of the mitotic spindle that segregates chromosomes during cell division and intracellular trafficking. During cell adhesion, integrins ...

N. gruberi normally lives as a little amoeba that only makes microtubules during cell division—in particular to build the mitotic spindle. However, when the amoeba is stressed, it can change into a ...

After chromosomes are aligned at equator, chromatids can finally segregate through depolymerization of attached microtubules and spindle pole movement. If this cycle is interrupted, the cell will not ...

Protein filaments, like microtubules, and molecular motors ... which is responsible for correct cell division. Research conducted by a team at the University of California, Santa Barbara, using ...

The spindle assembly checkpoint (SAC), composed of BUB and MAD proteins, ensures that chromosomes are properly attached to the spindle microtubules. In fungi and animals, at the start of cell division ...

Research from Umeå University paves the way for a quantitative data analysis method to study the cell division process in ...

A "pocket" on the protein cyclin B is responsible for ensuring that the steps of cell division take place in the correct order. Two studies by researchers at the University of Konstanz investigated ...

Developing effective treatments and understanding how the mechanism of the immune system have always been challenging for ...