Singed is the king of area denial, and Mordekaiser hates nothing more than being kept at bay. Singed's Poison Trail and Fling can zone Mordekaiser away from minion waves and crucial combat zones ...

Powerspikes: Mordekaiser got lots of small powerspikes ... or you can go for Blade of the Ruined King to sustain through skirmishes much longer. Trundle is strong from the get-go.