Here the authors show that NKp46 is required for the proliferation and cytotoxicity of type 1 innate lymphoid cells (ILCs) by activating the NF-κB signaling pathway and regulating IL-2Rα expression.

The study presents solid evidence on the cleavage of VgrG2B by Caspase 11 and the generation of fragments that inhibit activity of the NLRP3 inflammasome. This work should be of interest to ...

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Conclusion: YNJ attenuates LPS-induced ALI in mice by inhibiting pyroptosis of lung epithelial cells and macrophages via suppression of the NF-κB/NLRP3 pathway. Our findings provide novel insights ...

Jupiter, Florida, Jan. 13, 2025 (GLOBE NEWSWIRE) -- Jupiter Neurosciences, Inc. (NASDAQ: JUNS) (“Jupiter” or the “Company”), a clinical-stage pharmaceutical ...

Anti-CD146 antibodies or inhibitors may enhance chemosensitivity by attenuating NF-κB pathway activation and disrupting cell cycle progression. Early studies have shown that CD146-targeted therapies ...

Since version 1.7.4 the program has been renamed from "KeyNote" to "KeyNote NF". That way I hope it will be easier to locate it searching the web. To implement some of the new features included in ...