The preliminary data presented in this manuscript seem valuable. The data are currently incomplete and there are numerous technical concerns, some of which may arise from insufficient description of ...

One gene, GSK3β, weakens neuron defenses against oxidative stress. ApoE4 astrocytes cause hyperactivity and oxidative stress in neurons. This isn’t the first 3D model system involving hiPSC-derived ...

New research on nematodes reveals how glial cells maintain and monitor neuronal ... crucial supporting players detect and respond to neuron damage. Published in Nature Communications, the study ...

Glia (light green) respond to the loss of dendrite ... by which these crucial supporting players detect and respond to neuron damage. Published in Nature Communications, the study describes ...

Scientists have discovered that neural stem cells (NSCs) receive constant feedback from their daughter cells, influencing whether they remain dormant or activate to form new neurons and glia.

Neurons may get all the glory, but they would be nothing without glial cells. While brain cells do ... supporting players detect and respond to neuron damage. Published in Nature Communications ...

Interrupting signals exchanged between tumors and the nervous system could become a critical pillar of cancer care ...

However, the path to successful glia-to-neuron conversion is complex. A critical examination of the role of the RNA-binding protein PTBP1 revealed that its downregulation alone may not be ...

Brain cells called glia play various supporting roles to keep the system running smoothly. Between the axon of a transmitting neuron and the dendrite of a receiving neuron is a gap called the ...

A pathological hallmark of MSA is the accumulation of the protein α-synuclein within glia, the support cells of the central nervous system, and neuron loss in multiple brain regions. MSA affects at ...

Astrocytes are the largest and most prevalent type of glial cell in the central nervous ... discover an astrocyte-to-neuron hydrogen peroxide signalling cascade, which is crucial for long-term ...