Glaucoma is a complex and multifactorial neurodegenerative disorder primarily characterized by the progressive loss of retinal ganglion cells (RGCs) and their axons, leading to irreversible visual ...

In contrast, downregulated miRNAs were more strongly associated with the signaling of neurotrophin TRK receptors and Toll-like receptor signaling pathways, such as the TRIF-dependent pathway and ...

This influx of calcium at the contact site attracts and activates a kinase called CaMKII, a protein known to be important in ...

A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked into a cancer cell. The work reveals a new signaling mechanism that could be exploited for delivering other ...

A new study shows how an anticancer drug triggers an "outside in" signal that gets it sucked into a cancer cell. The work, ...

7 refine our understanding of the signaling effects of oncogenic KRAS. Rather than activating multiple effectors, mutant KRAS signals preferentially through the RAF–MEK–ERK pathway ...

This discrepancy indicates that the etching procedure introduced extraneous conductive pathways unrelated to the VHE, thereby explaining why a reduced band gap had been observed in prior ...

In a significant boost to rail safety, Indian Railways has successfully upgraded its signalling system at Shakurbasti in New Delhi, replacing one of the country's oldest mechanical interlocked yards.

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