Frontiers5d
Commonly Used Anesthesia/Euthanasia Methods for Brain Collection Differentially Impact MAPK Activity in Male and Female C57BL/6 Mice
The three classical MAPK subfamilies, extracellular signal-regulated kinase 1 and 2 (ERK1/2), c-Jun N-terminal kinase (JNK), and p38 kinase have been linked to various neurological disorders often in ...
SciELO3d
Lactylated histone H3K18 as a potential biomarker for the diagnosis and prediction of the severity of pancreatic cancer
Increased histone H3 Lysine-18 lactylation (H3K18la) levels have been reported in various diseases. For instance, elevation of H3K18la protein levels was associated with sepsis and septic shock. 14 ...
Frontiers5d
Enterobacterial LPS-inducible LINC00152 is regulated by histone lactylation and promotes cancer cells invasion and migration
Gut microbes participate in pathogenesis by interacting with the host genome through epigenetic mechanisms, such as long non-coding RNAs. However, the mechanisms by which the microbiota induce ...