PTI Sindh president, Haleem Adil Sheikh, during a press conference at Insaf House, announced a province-wide protest campaign against the 'stolen mandate' from February 1 to February 8. He also ...

The Lahore High Court (LHC) has sought response from the deputy commissioner (DC) of Lahore after the opposition Pakistan Tehreek-e-Insaf (PTI) party filed a petition requesting permission to hold ...

Biologists have uncovered a surprising connection between the way plants grow and how they defend themselves against ...

A new study shows how an anticancer drug triggers an 'outside in' signal that gets it sucked into a cancer cell. The work reveals a new signaling mechanism that could be exploited for delivering other ...

Efficient method for directly modifying endogenous plant proteins remains unavailable. Here, the authors develop a Targeted Condensation-prone-protein Degradation (TCD) strategy using a ...

Ubiquitin is an intracellular signalling molecule that is conjugated to various proteins. Ubiquitin conjugation to itself yields Lys- or Met-conjugated chains, thus expanding its repertoire of ...

Figure 1 TLR signaling pathway in innate immune cells. TLR5, TLR4, and the heterodimers of TLR2–TLR1 or TLR2–TLR6 prefer to recognize the membrane components of pathogens at the cell surface, whereas ...

Recent studies have shown that genomic material from microbial pathogens induces the STING signaling pathway for the production of immune factors to attenuate infection. In contrast, microbial ...

PREVIEW is an eight-issue subscription publication that provides expert, plain-language analysis of all cases given plenary review by the Supreme Court in advance of oral argument. Preview issues 1-7 ...

Genetic alterations may help mosquitoes adjust to climate change, shifting the distribution of mosquito-borne disease in a warming planet.