An innovative organoid model mirrors the pancreas' complexity, generating all three key cell types to explore development and ...

Our perspective about glucose toxicity as it pertains to the pancreatic ß-cell is that the characteristic decreases in insulin synthesis and secretion are caused by decreased insulin gene expression.

Figure 1: Mitochondrial involvement in cell death. Mitochondria are organelles with two well-defined compartments: the matrix, surrounded by the inner membrane (IM), and the intermembrane space ...

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