The divergence of new genes and proteins occurs through mutations that modulate protein function. The effects of these mutations are pleiotropic, thus imposing trade-offs between selection ...

The SYNGAP1 gene, which supports the production of a protein called SynGAP (Synaptic Ras GTPase-Activating Protein), is known ...

For example, they uncovered the function of TMEM251, a gene that has been linked to a rare genetic lysosomal storage disease. The team found that it is required for trafficking enzymes to lysosomes.

Gene expression regulation in cancer and cellular functions. ScienceDaily . Retrieved February 14, 2025 from www.sciencedaily.com / releases / 2025 / 01 / 250124151353.htm ...

Get Instant Summarized Text (Gist) A new approach, PERISCOPE, integrates Cell Painting and Optical Pooled Screening to enable genome-scale CRISPR screens, linking cell morphology to gene function ...