In a recent study, researchers demonstrated that Z526, a novel dithiocarbamate-like compound, mitigates cancer-associated cachexia (CAC) both in vitro and in vivo.

The mechanism of enzyme catalysis is similar in principle to ... which involves cholesterol and vitamin K. Protein kinase R-like endoplasmic reticulum kinase-phosphorylated adenylosuccinate ...

Correlation of small structural changes induced by ligand binding with protein ... catalytic constant of the enzyme 11. In chemotaxis, the aspartate receptor becomes an inhibitor of the kinase ...

This ion not only plays structural and catalytic roles in regulating thousands of metalloproteins ... results in activation of Zip7 through its phosphorylation by the protein kinase CK2, which leads ...

The lab recently determined that what is important is not formation of the fusion, but that the formation results in an increase of the amount of PRKACA—the catalytic subunit of protein kinase A ...

This paper reviews the research progress of the conserved herpesvirus protein kinase UL13 in immune escape and viral replication to provide a basis for elucidating the pathogenic mechanism of ...

Get Instant Summarized Text (Gist) Artificial motors have been developed to mimic muscle proteins, converting chemical energy into mechanical work. These nanoscale rotary motors, embedded in ...

"The addition of water alters the reaction mechanisms, promoting pathways that enhance catalytic activity while suppressing coke formation," explains Dr. Ro. "This dual role improves process ...

"These findings illuminate a critical mechanism that connects local synaptic ... This research focuses on the cAMP-response element binding protein (CREB), a transcription factor known to regulate ...

The researchers investigated the effect of different conducting polymers (PANI, PPy, and poly(3,4-ethylenedioxythiophene) (PEDOT)) on the mechanism of CP@CdS core-shell nanorods. The results show that ...

The results highlight an important physiological function of PGAM in the differentiation and suppressive activity of Treg cells by regulating serine synthesis. This role is proposed to intersect with ...

On the other hand, mechanisms of acquired resistance to 'pathway-targeted' drugs, such as the various clinically active kinase inhibitors, have been somewhat more straightforward to elucidate and ...