Reprogramming of fibroblasts from patients with Mendelian ... into iPS cells has already had major effects on research in stem cell biology and regenerative medicine. Is this technology mature ...

Direct cardiac reprogramming, a process that bypasses the intermediate stem cell stage, allows fibroblasts to be converted into iCMs. While this approach holds significant promise, scientists have ...

Cardiac reprogramming and stem cell therapy are innovative fields ... Recent research has focused on various methods to convert cardiac fibroblasts (the cells that form scar tissue after heart ...

Scientists first developed the ability to reprogram somatic cells into pluripotent stem cells—cells that could give rise to any of the body’s cells types—in 2006. However, the technique has required ...

Members of Theme Six are developing stem cell and cellular reprogramming strategies to treat cardiovascular diseases such as infarction in situ. The goal is to use viral vectors to induce ...

The journey from panda fibroblasts ... first tried reprogramming conditions that worked for other species, they met their first hurdle. “Surprisingly, when we used the mouse and human conditions, they ...

Pancreatic cancer is fueled by connections to the nervous system. This is reported by scientists from the German Cancer ...

Reprogramming Cells that are reprogrammed into stem cells from specialized cells are called induced ... By introducing the needed gene regulators into the cells (into for example fibroblasts) in the ...

The researchers also did not first reprogram the skin cells into pluripotent stem cells—something that ... aortic valves via transdifferentiating fibroblasts into valvular endothelial cells ...