Yale researchers have created "Ochre," a genomically recoded organism that enables the production of synthetic proteins with ...

Our study identifies oncofetal reprogramming of neoplastic stem cells, driven by the transcription factors YAP and AP-1, as a critical driver of phenotypic heterogeneity, lineage plasticity and ...

Inflammatory bowel diseases (IBDs), which include ulcerative colitis (UC) and Crohn’s disease (CD), are chronic conditions ...

Every cell in our body contains the entire genetic program to become any cell type. Such cells are called “stem cells”. But once turned into a muscle cell, it can never evolve into a neuron. So, we ...

Life relies on the storage and transmission of information. In complex organisms, this information exists in two primary forms: the genome and the epigenome. While genetic information remains largely ...

People attending a football match will be asked to sign up to a stem cell register in the hope of finding a donor for a local man. Marshall Davies, 21, from Telford, was diagnosed with a rare and ...

The resulting PCL–Zn (PZ) nanofibers effectively guided the growth of NIH3T3 fibroblasts for 7 days, forming a fibroblast cell sheet. The PZ fibers were decellularized to remove autologous and ...

This is a valuable report of a spatially-extended model to study the complex interactions between immune cells, fibroblasts, and cancer cells, providing insights into how fibroblast activation can ...

Department of Orthopaedics, Xijing Hospital, Fourth Military Medical University, Xi’an 710032, China Department of Biochemistry and Molecular Biology, Fourth Military Medical University, Xi’an 710032, ...