Poxviruses are a family of large, double-stranded DNA viruses, which include variola virus (smallpox ... of host cells and form large DNA-filled replication compartments. To evade antiviral ...

[93] Live-virus smallpox vaccines are traditionally ... Lister Historical experience in the Intensified Smallpox Eradication Programme Replication-deficient, highly attenuated vaccinia virus ...

First-generation smallpox vaccines have a long ... Highly attenuated, replication-defective vaccinia MVA sacrifices degrees of immunogenicity and efficacy for its theoretically improved safety ...

Obeying instructions from the virus, the newly infected cell sprouts ... making it a factory for replication. The discovery that the coronavirus also makes the zombie cells sprout tentacles ...

Examples include the highly successful smallpox, measles ... tetanus, hepatitis B virus and flu), which require multiple doses and regular boosting, live attenuated vaccines provided as single ...

The Human Virome Program will analyze samples from thousands of volunteers in an effort to understand how viruses affect health.

By William J. Broad In 1999, William J. Broad and two colleagues wrote a comprehensive article on the past, present and future of the smallpox virus. Feb. 12, 2025 President Trump’s order that ...

Announcing a new article publication for Zoonoses journal. Vaccinia virus (VACV) confers cross-protective immunity against variola virus, the causative agent of smallpox, and has therefore been ...

Announcing a new article publication for Zoonoses journal. Vaccinia virus (VACV) confers cross-protective immunity against the variola virus, the causative agent of smallpox, and has therefore been ...