In frame translation initiation sites within coding sequences drive the expression of N-terminally truncated proteoforms.

The ribosome is a large assembly of proteins and ribosomal RNAs (rRNAs) that functions to translate messenger RNAs (mRNAs) into proteins. The ribosome catalyzes the assembly of amino acids into ...

Imagine a breakthrough in cancer treatment where only malignant cells are targeted, sparing healthy host cells; or patients with abnormal protein synthesis are treated to produce a healthy protein.

An artificial-intelligence network trained on a vast trove of sequence data is a step towards designing completely new ...

A guardian molecule ensures that liver cells do not lose their identity. The discovery is of great interest for cancer medicine because a change of identity of cells has come into focus as a ...

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