Frontiers5d
The Two NF-κB Pathways Regulating Bacterial and WSSV Infection of Shrimp
Bacterial infection can be recognized by Toll and IMD pathways, which activate two NF-κB transcription factors, Dorsal and Relish, respectively, to eventually lead to boosting the expression of ...
Frontiers5d
Cationic Arginine-Rich Peptides (CARPs): A Novel Class of Neuroprotective Agents With a Multimodal Mechanism of Action
The AMPK pathway is a major energy sensing system that monitors ... Similarly, different classes of endogenous anti-microbial peptides (e.g., defensins, cathelicidins, bactenecin) have been derived ...
FierceBiotech1d
New AI-discovered protein compounds kill bacteria and fungi infecting mice: study
Researchers have used artificial intelligence to identify 25 new protein compounds that can kill bacteria and fungi, ...
Science Daily2d
Major driver of inflammatory pathology in autoimmune and chronic inflammatory diseases
Researchers discovered a previously unknown mechanism that may drive tissue damage and a new target for drug discovery.
EurekAlert!2d
Researchers discover a major driver of inflammatory pathology in autoimmune and chronic inflammatory diseases
Mass General Brigham researchers discovered a previously unknown mechanism that may drive tissue damage and a new target for drug discovery ...
Nature5d
Granulocyte colony-stimulating factor and neutrophils—forgotten mediators of inflammatory disease
11 Calgranulin A (S100A8) and calgranulin B (S100A9) are secreted following cellular activation or necrosis, have antimicrobial activity, and can induce neutrophil chemotaxis and adhesion.
C&EN6d
Pathway-Dependent Catalytic Activity of Short-Peptide-Based Metallozyme: From Promiscuous Activity to Cascade Reaction
Department of Chemical Sciences & Centre for Advanced Functional Materials, Indian Institute of Science Education and Research (IISER) Kolkata, Mohanpur, West Bengal 741246, India ...