Tau aggregates appear inside synapses from human brain samples with Aβ pathology. The method can be adapted to study other synaptic proteins. As reported in Cell Chemical Biology on January 23, first ...
Furthermore, changes in efficacy at excitatory synapses are thought to ... by glutamate release from the same terminal? Is this a stable endpoint of synaptic plasticity, or are presynaptic release ...
Here, the authors' model - including AP annihilation at a synaptic terminal - is used to predict the amplitude ... This happens even though there is no gap junction, at chemical synapses. The ...
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The synaptic mechanism of working memory proposes that information is stored as hidden states in the form of facilitated neuronal synapse connections ... by the influx of calcium into the synaptic ...
Neurons generate and propagate electrical pulses called action potentials which annihilate on arrival at the axon terminal ... Basket cell - Purkinje cell synapse. It is able to predict ephaptic ...
For the new study, the researchers investigated a specific type of connection between neuronal cells, called electrical synapses, which differs from the more widely studied chemical synapses ... adapt ...
Researchers have identified a key pathway that links how neurons send signals to each other, or synaptic activity ... neurons receive input from their synapses, which are located in distant ...
Researchers have achieved total chemical synthesis of the psychoactive compound ibogaine and its analogs from pyridine. The discovery will make it easier to explore the therapeutic possibilities of ...
C-terminal amidation is a PTM that involves the addition of an amid group to the C-terminus of a peptide or protein. Currently there is no direct evidence to suggest that C-terminal amidation of ...
At first, a brain chemical called dopamine is essential for young males to master this behavior. But as they gain experience, the chemical grows less important in promoting aggression, a new study ...