The dengue virus has a roughly spherical shape. Inside the virus is the nucleocapsid, which is made of the viral genome and C proteins. The nucleocapsid is surrounded by a membrane called the ...

More specifically we seek to know how different viruses assemble, uncoat, and interact with host cells to promote infection ... Research interests: assembly and structure determination of viruses, ...

Now, researchers used cryoelectron microscopy (cryo-EM) to elucidate the structure ... is published in Cell in the paper, “Structural and functional analysis of the Nipah virus polymerase ...

which infect more cells. The spread of the dengue virus results in viremia, which is a high level of the virus in the bloodstream. To fight the infection, the immune system produces antibodies to ...

and infect cells. The work provides a detailed three-dimensional picture of the virus's polymerase and its key features. Understanding the structure and behavior of this critical piece of the ...

After entering host cells ... was an intricate RNA structure near the critical "frameshift site" in the viral genome. This frameshift site is essential for the virus to produce the correct ...