Both fluorescence and differential interference contrast ... microscope equipped with a Hamamatsu ORCA-ER digital cooled camera. The representative fields shown in the images were obtained from a ...

By contrast, standard assays typically require ... Some require only a light microscope and cell counting, while others are based on EIA technology. These include: Cytospheres (Coulter), Dynabeads ...

If the inputs are images generated by a label-free contrast ... depletion (STED) microscopy equivalent images (Wang et al., 2019). To our knowledge, a concept that has not yet been realized is ...

After the infection, cells were fixed with 4% paraformaldehyde (Electron Microscopy Sciences ... 30% deionised formamide, 0.1% yeast tRNA (Invitrogen, 15401-011), 1% (v/v) RNase inhibitor (NEB, M0314S ...

Cancer cells work together to source nutrients from their environment—a cooperative process that was previously overlooked by scientists but may be a promising target for treating cancer.

Protein translocation is an essential, nano-scale dynamic process that facilitates the movement of proteins across cellular ...

Due to proteostasis stress induced by aging or disease, misfolded proteins can form toxic intermediate species of aggregates and eventually mature into less toxic inclusion bodies (IBs). Here, using a ...

As cancer cells adapt to therapies ... As reported in Biophotonics Discovery, the team developed a novel microscopy technique that uses a standard fluorescence microscope in combination with ...

Scientists have completed construction of the final chromosome in the worlds' first synthetic yeast genome following ... like copper metabolism and how cells divide their genetic material.

In other words, the molecular components of the granules were undergoing phase transitions like those ... blobs that appear in yeast cells, contain condensates made of an RNA-binding protein ...

Exploratory study of TAS-102 combined with intermittent administration of fruquintinib in the treatment of third-line metastatic colorectal cancer. This is an ASCO Meeting Abstract from the 2025 ASCO ...