Primary antibodies were used at a 1:200 dilution: p-Y-576/p-Y-577–FAK (focal adhesion kinase) (Cell Signaling, Boston, MA); FAK, actin, PECAM-1, β-catenin (Santa Cruz, Santa Cruz, CA ...

β-catenin is an integral part of adherens junctions and a central component of canonical Wnt signaling. Here, the authors addressed the role of β-catenin in fibroblasts for the development of SSc ...

TNF, tumor necrosis factor; AJ, adherens junctions; TJ, tight junctions ... S1P and S1PR (1–3) are highly expressed in the liver and can act through various signaling pathways. For instance, the Spns2 ...

Putative model describing the signaling pathways and other genes suggested to ... or they do not obviously fit in the pathways with current knowledge. AJ, adherens junction; ECM, extracellular matrix.

However, the study provides limited new insights into the relationship between retinal lamination defects and overall retinal function. Neural lamination is a common feature of the central nervous ...

Today will see patchy cloud and bright spells. It will remain dry throughout much if the day, but light spells of rain will move in towards the evening. A chilly day. Tonight Tonight will see ...

Travelling through one of London’s most notorious junctions could soon be different if plans to shake it up go ahead. The ‘Shoreditch Triangle’ area in east London was named the capital’s ...

This influx of calcium at the contact site attracts and activates a kinase called CaMKII, a protein known to be important in ...

New research shows that a network of subcellular structures similar to those responsible for propagating molecular signals that make muscles contract are also responsible for transmitting signals in ...

Lancashire Constabulary, Lancashire Fire & Rescue Service and North West Ambulance Service are all in attendance at the crash between junction 32 for the Broughton Interchange and M55 and junction ...

Summary: New research reveals that brain cells use a muscle-like signaling mechanism to relay information ... of periodically arranged endoplasmic reticulum-plasma membrane (ER-PM) junctions tiling ...