Apr 12, 2016 · Their brains were then imaged inside an fMRI scanner to visualize their brain activity. “Under normal conditions, information from our eyes is processed in a part of the brain at the back of the...

We aimed to evaluate the effect of Lysergic acid diethylamide (LSD) on the pain neural network (PNN) in healthy subjects using functional magnetic resonance imaging (fMRI). Twenty healthy volunteers participated in a balanced-order crossover study, ...

Feb 15, 2021 · Focusing on the two fundamental network properties of integration and segregation, here we combined graph theory and dynamic functional connectivity from resting-state functional MRI to examine time-resolved effects of LSD on brain networks properties and subjective experiences.

Feb 13, 2019 · Overall, the data revealed that LSD alters connectivity within the brain’s cortico–striato–thalamo-cortical (CSTC) regions in two primary ways. First, it increased effective connectivity from the thalamus to the posterior cingulate cortex (PCC) when pretreatment with the ketanserin occurred.

Jan 28, 2019 · We used spectral dynamic causal modeling (DCM) for resting-state fMRI data. Fully connected DCM models were specified for each treatment condition to investigate the connectivity between the following areas: thalamus, ventral striatum, posterior cingulate cortex, and temporal cortex.

Apr 11, 2016 · Twenty healthy participants attended two scanning days (LSD and placebo) at least 2 wk apart in a balanced-order, within-subjects design. Sessions included an fMRI followed by a MEG scan, each lasting 75 min. Data were acquired during eye-closed, task-free, “resting state” conditions.

No correlations were found between past LSD use and the acute effects of LSD on functional magnetic resonance imaging (fMRI) study outcomes across subjects with prior LSD use (Speth et al, 2016; Tagliazucchi et al, 2016).

Jul 17, 2024 · In the LSD session, functional connectivity of PO-left with FP-left and FP-right was observed. The effective connectivity between left anterior insula cortex (lAIC)-lAIC, lAIC-dorsolateral prefrontal cortex (dlPFC) and secondary somatosensory cortex (SII)-dlPFC were significantly different.

Mar 11, 2025 · This approach was followed to demonstrate that LSD increases the complexity of spontaneous brain activity as assessed via fMRI 26, an observation consistent with previous studies showing an ...

This study provides new insights into the neural processes underlying the brain network reconfiguration induced by LSD. It also identifies a topographical relationship between opposite effects on brain functioning and the spatial distribution of different 5-HT receptors.