A triazole is a heterocyclic compound featuring a five-membered ring of two carbon atoms and three nitrogen atoms with molecular formula C 2 H 3 N 3. Triazoles exhibit substantial isomerism, depending on the positioning of the nitrogen atoms within the ring.

Among the nitrogen-containing heterocyclic compounds, triazoles emerge with superior pharmacological applications. Structurally, there are two types of five-membered triazoles: 1,2,3-triazole and 1,2,4-triazole.

Triazole, comprising three nitrogen atoms and two carbon atoms, is divided into two isomers 1,2,3-triazole and 1,2,4-triazole. Compounds containing a triazole are one of the significant heterocycles that exhibit broad biological activities, such as ...

1,2,3-Triazole is one of a pair of isomeric chemical compounds with molecular formula C 2 H 3 N 3, called triazoles, which have a five-membered ring of two carbon atoms and three nitrogen atoms. 1,2,3-Triazole is a basic aromatic heterocycle.

Apr 22, 2021 · Triazoles are the five-membered heterocycles with three nitrogen atoms and two carbon atoms. There exist two tautomeric forms of triazole, i.e., 1, 2, 3-triazole and 1, 2, 4-triazole, depending upon the position of the nitrogen atoms in the rings.

Triazole is a five membered ring with three nitrogen and two carbon atoms. Depending on the disposition of the five atoms, triazoles exist in two isomeric forms, namely 1,2,3- and 1,2,4-triazoles.

Apr 25, 2022 · Among the nitrogen-containing heterocyclic compounds, triazoles emerge with superior pharmacological applications. Structurally, there are two types of five-membered triazoles: 1,2,3-triazole...

May 3, 2024 · Triazole demonstrates distinctive physicochemical properties, characterized by weak basicity, various dipole moments, and significant dual hydrogen bond acceptor and donor capabilities. These features are poised to play a pivotal role in drug–target interactions.

Triazoles are critical scaffolds in medicinal chemistry. They are part of numerous drugs due to their unique pharmacological properties. For instance, triazoles serve as core structures in antifungal agents such as fluconazole and itraconazole.

Triazole, also known as pyrrolidazole, is an organic heterocyclic compound containing a five-membered unsaturated ring structure consisting of three nitrogen atoms and two carbon atoms [1]. Triazole has a good curative effect, low toxicity, and excellent pharmacokinetics in drug research and development, with outstanding contributions to the ...