Adeno-associated viruses (AAV) are small viruses that infect humans and some other primate species. They belong to the genus Dependoparvovirus, which in turn belongs to the family …

Apr 3, 2024 · Adeno-associated virus (AAV) has emerged as a pivotal delivery tool in clinical gene therapy owing to its minimal pathogenicity and ability to establish long-term gene expression in …

Adeno-associated virus (AAV) is a non-enveloped virus that can be engineered to deliver DNA to target cells, and has attracted a significant amount of attention in the field, especially in clinical …

Jan 6, 2025 · Adeno-associated viruses (AAV) are non-enveloped, single-stranded DNA viruses heavily studied for their use in gene therapy. The virus belongs to a subset of the Parvoviridae …

Discovered as a contaminant of adenovirus stocks in the 1960s, adeno-associated virus (AAV) is a mono-stranded DNA virus that depends on helper factors to replicate. Even though AAV is …

Adeno-associated viruses (AAV) are single stranded DNA viruses that have not been found to cause pathology in humans. The AAV is dependent on helper viruses for replication and for …

Adeno-associated virus gets its name because it is often found in cells that are simultaneously infected with adenovirus. AAV are Parvoviridae: icosahedral, 20-25 nm in diameter; single …

Early experiments characterized a virus that replicated poorly, if at all, in human cells in the absence of Ad.

Feb 1, 2019 · Adeno-associated virus (AAV) is recognized by glycosylated cell surface receptors of the host. This triggers internalization of the virus via clathrin-mediated endocytosis.

May 6, 2005 · The initial discovery of adeno-associated virus (AAV) mixed with adenovirus particles was not a fortuitous one but rather an expression of AAV biology. Indeed, as it came …