β-Lactam antibiotics (beta-lactam antibiotics) are antibiotics that contain a β-lactam ring in their chemical structure. This includes penicillin derivatives ( penams ), cephalosporins and cephamycins ( cephems ), monobactams , carbapenems [ 1 ] and carbacephems . [ 2 ]

A β-lactam (beta-lactam) ring is a four-membered lactam. [1] A lactam is a cyclic amide, and beta-lactams are named so because the nitrogen atom is attached to the β-carbon atom relative to the carbonyl. The simplest β-lactam possible is 2-azetidinone. β-lactams are significant structural units of medicines as manifested in many β-lactam ...

β-内酰胺类抗生素（β-lactams）系指化学结构中具有β-内酰胺环的一大类抗生素，包括临床最常用的青霉素与头孢菌素，以及新发展的头霉素类、硫霉素类、单环β-内酰胺类等其他非典型β-内酰胺类抗生素。

β-內醯胺抗生素（β-lactam antibiotics）是化学结构中具有β-内酰胺环的一大类抗生素，包括青霉素及其衍生物、頭孢菌素、 单酰胺环类 （ 英语 ： monobactam ） 、碳青霉烯和青霉烯类酶抑制剂等。

Jun 4, 2023 · Beta-lactam antibiotics are used in the management and treatment of bacterial infections. This activity will highlight the mechanism of action, adverse event profile, and other key factors (e.g., off-label uses, dosing, pharmacodynamics, pharmacokinetics, monitoring, relevant interactions) pertinent for members of an interprofessional ...

β-Lactam antibiotics are bactericidal agents that interrupt bacterial cell-wall formation as a result of covalent binding to essential penicillin-binding proteins (PBPs), enzymes that are involved in the terminal steps of peptidoglycan cross-linking in …

Beta-lactamases are a diverse class of enzymes produced by bacteria that break open the beta-lactam ring, inactivating the beta-lactam antibiotic. Some beta-lactamases are encoded on mobile genetic elements (eg, plasmids); others are encoded on chromosomes. Beta-lactamase production is among the most clinically important mechanisms of ...

Dec 15, 2020 · The β-lactam antibiotics is a family of bactericidal drugs structurally-related containing the β-lactam ring in their chemical structure. They are classified in penicillins, cephalosporins, carbapenems, penems (also known as thiopenems) and monobactams.

Jun 24, 2016 · β-Lactams are the most widely used class of antibiotics. Since the discovery of benzylpenicillin in the 1920s, thousands of new penicillin derivatives and related β-lactam classes of cephalosporins, cephamycins, monobactams, and carbapenems have been discovered.

β-内酰胺类抗生素（β-lactam antibiotics）是指化学结构中含有β-内酰胺环的一类抗生素。 特点： 抗菌谱广; 抗菌活性高; 毒性低; 疗效好。