25I-NBOMe, also known as 2C-I-NBOMe, Cimbi-5, and shortened to "25I", is a psychedelic drug of the phenethylamine, 2C, and NBOMe (25-NB) families. Since 2010, it has circulated in the …

25I-NBOMe (also known as 2C-I-NBOMe, NBOMe-2C-I, Cimbi-5, Smiles, and one of many drugs referred to as N-Bomb) is a novel psychedelic substance of the phenethylamine chemical …

25I-NBOMe enhanced extracellular level of DA, 5-HT, and glutamate in the rat frontal cortex (Fig. 1a, b, c). It also increased cortical 5-HT and 5-HIAA tissue content (Fig. 3a, b). In addition, 25I …

25I-NBOMe can be fatal at heavy doses. [1] It is strongly discouraged to take large amounts of this substance or to insufflate (snort) it. Please see this section for more details. Psychoactive …

In this report, we aimed to systematically review analytically confirmed cases of NBOMe-related toxicities. Relevant scientific articles were identified from MEDLINE (PubMed) database …

Jun 18, 2018 · 25I-NBOMe is a designer drug that has only been around since 2010. Reporting on traumatic or negative experiences, hospitalizations, and deaths has been spotty at best, but it …

NBOMes such as 25I-NBOMe produces visual effects like LSD, but unlike LSD, 25I has an unpredictable safety profile and seemingly random negative effects. Refer to LSD flyer for …

25I-NBOMe has its main activity as 5HT2 receptor agonism, which is associated with increased dopaminergic activity in the brain. Hallucinations, delusions, anxiety symptoms and …

Subjectively speaking, LSD and 25I-NBOMe have similar effects, but 25I-NBOMe generally produces a heavier visual trip and a less clear headspace. Many individuals report more …

Feb 12, 2025 · 25i, also known as 25I-NBOMe, is characterized by its high affinity for serotonin receptors, particularly the 5-HT2A receptor, defining its potent hallucinogenic properties.