Sep 15, 2020 · Herein, we propose a powerful two-dimensional hybridization chain reaction (2D HCR) strategy for amplified sensing and imaging of intracellular mRNA. The basis is the …

Jun 22, 2020 · Here, we describe an aptamer-trigger-clamped hybridization chain reaction (atcHCR) method for the capture of CTCs by porous 3D DNA hydrogels. The 3D environment …

Motivated by this knowledge, we have engineered a compact and clamped cascaded DNA circuit for specifically discriminating cancer cells from normal cells via the amplified multi-microRNA …

May 15, 2016 · R1 was the responses of the first dimension HCR and R2 was the responses of the 2D HCR. Measurements were performed at 25 °C. Here we report a proof-of-concept …

Aug 17, 2020 · Herein, we propose a powerful two-dimensional hybridization chain reaction (2D HCR) strategy for am-plified sensing and imaging of intracellular mRNA. The basis is the …

Jul 17, 2017 · In a typical HCR, an analyte initiates the cross-opening of two DNA hairpins, yielding nicked double helices that are analogous to alternating copolymers. As an efficient …

Hybridization chain reaction (HCR) provides a feasible solution for nucleic acid detection without target amplification. By highly specific sandwich hybridization, target RNA can be directly …

Aug 17, 2020 · Herein, we propose a powerful two-dimensional hybridization chain reaction (2D HCR) strategy for am-plified sensing and imaging of intracellular mRNA. The basis is the …

Confocal laser scanning microscopy images of mRNA based on 1D HCR without and with MnO 2 nanosheets.

Herein, the authors leverage DNA tetrahedral frameworks (DTFs) modified on the wireless portable electrodes to effectively capture 3D hybridization chain reaction (HCR) amplifiers for …