
3T3-L1 - Wikipedia
3T3-L1 is a sub clonal cell line derived from the original 3T3 Swiss albino cell line of 1962. The 3T3 original cell line was isolated from a mouse embryo and propagated for this specific line of …
Protocol for effective differentiation of 3T3-L1 cells to adipocytes
Jun 1, 2012 · In this note, we present a detailed procedure for highly effective and reproducible 3T3-L1 cell differentiation. Due to their potential to differentiate from fibroblasts to adipocytes, …
3T3-L1 adipocytes display phenotypic characteristics of multiple ...
Differentiation of multi-potential 3T3-L1 fibroblasts into lipid laden adipocyte-like cells is one of the most common in vitro models used in the study of adipocyte biology.
A Detailed Guide to 3T3-L1 Adipogenic Differentiation
Jan 16, 2025 · The 3T3-L1 cell line, a mouse embryonic fibroblast cell line, was first isolated by Green and Kehinde in 1974. Due to its ability to differentiate into adipocyte-like cells in vitro, it …
3T3-L1 Cell Line: A Key to Understanding Obesity - Cytion
The 3T3-L1 cell line is commonly used to study adipocyte biology, adipocyte cell differentiation, and related cellular and molecular mechanisms. The differentiation of 3T3-L1 cells into …
3T3-L1 Cells Lose Contact Inhibition and Adipogenic Potential
We find that newly thawed, contact inhibited 3T3-L1 cells are adipogenic, but they lose adipogenic potential after being maintained in culture at confluence and losing contact inhibition. Thus, the …
Modelling the gene expression and the DNA-binding in the 3T3-L1 ...
3T3-L1 is a mouse pre-adipocyte cell line which can be induced to differentiate into mature adipocytes when it is treated with a chemical cocktail. The most commonly used variant of …
Robust and well-characterized, 3T3-L1 pre-adipocytes differentiate and form fat pads indistinguishable from normal adipose tissue when injected into mice. In this protocol, …
3T3-L1 Cell Line - an overview | ScienceDirect Topics
The 3T3-L1 cell-line is a widely used model system for the analysis of adipocyte differentiation. The characteristic of this cell line is its ability to differentiate into mature adipocytes upon …
The Use of 3T3-L1 Murine Preadipocytes as a Model of …
Dec 11, 2018 · The 3T3-L1 murine preadipocyte cell line is a commonly used tool for analysis of the subcellular pathways involved in preadipocytic cell differentiation (a process also …
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