5-MeO-DET or 5-methoxy-N,N-diethyltryptamine is a hallucinogenic tryptamine. 5-MeO-DET inhibits serotonin reuptake with an IC 50 value of 2.4 μM and activates 5-HT 2A receptors with an EC 50 value of 8.11 nM. [1][2][3][4][5][6][7] Low dosages (0.5–1 mg) are reported to produce a relaxing body high and mild entheogenic effects.

Feb 21, 2015 · Here is a simple, easy to make compound that lies in-between the lower homologue, 5-MeO-DMT (active at 10+ milligrams by any parenteral route) and 5-MeO-DIPT (active at 10+ milligrams orally). The most rudimentary logical demands, yea, screams, that 5-MeO-DET should be active at 10+ milligrams, probably also by the oral route.

5-MeO-DMT, also known as 5-methoxy- N, N -dimethyltryptamine, is a substituted tryptamine derivative. It is the 5- methoxylated derivative of N, N -dimethyltryptamine (DMT), the N, N - dimethylated derivative of 5-methoxytryptamine (5-MT; mexamine), and the O -methylated derivative of bufotenin (5-HO-DMT).

5-MeO-DMT is a natural tryptamine that requires the presence of a MAOI to produce psychedelic effects . 5-MeO-DMT is ingested but unpublished reports describe inhalation as a common mean of consumption with effects appearing within 60 sec and lasting 5–20 min .

Mar 14, 2024 · Thus, this study aims to elucidate the impact of amino-terminal modifications to the 5-MeO-DMT molecule on its interactions with serotonin receptors and transporters, as well as its...

5-MeO-DPT, also known as 5-methoxy-N,N-dipropyltryptamine, is a psychedelic and entheogenic designer drug of the tryptamine family related to dipropyltryptamine (DPT) and 5-MeO-DMT. [1] [2] [3] [4]

Feb 26, 2016 · 5-MeO-DMT—short for 5-Methoxy-N,N-Dimethyltryptamine—looks just like DMT on both a macro and micro level, with a few extra atoms attached (which is what “5-MeO” in the name tells us). That slight change makes all the difference, though.

Take a trip into the world of tryptamines psychedelics with our 5-MeO-DET Research Powder. This compound was synthesized by renowned chemist Alexander Shulgin and offers a unique research opportunity into the effects of tryptamines.

The abuse liability profile of three synthetic hallucinogens, N,N-diisopropyltryptamine (DIPT), 5-N,N-diethyl-5-methoxytryptamine (5-MeO-DET), and 5-methoxy-α-methyltryptamine (5-MeO-AMT), was tested in rats trained to discriminate hallucinogenic and psychostimulant compounds, including cocaine, methamphetamine, 3,4 ...

Jun 16, 2024 · Explore the sophisticated methodologies and best practices in synthesizing the entheogen 5-MeO-DET, a powerful psychedelic compound known for its profound effects.