Dec 25, 2024 · PRKAA1 (Protein Kinase AMP-Activated Catalytic Subunit Alpha 1) is a Protein Coding gene. Diseases associated with PRKAA1 include Mitochondrial Disease and Wolff-Parkinson-White Syndrome. Among its related pathways are Gene expression (Transcription) and Transmission across Chemical Synapses.

5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that plays a role in cellular energy homeostasis, largely to activate glucose and fatty acid uptake and oxidation when cellular energy is low.

AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation.

Dec 25, 2024 · PRKAA2 (Protein Kinase AMP-Activated Catalytic Subunit Alpha 2) is a Protein Coding gene. Diseases associated with PRKAA2 include Ischemia and Peutz-Jeghers Syndrome. Among its related pathways are Selective autophagy and Gene expression (Transcription).

5′-adenosine monophosphate (AMP)-activated protein kinase (AMPK) is an evolutionarily conserved serine/threonine kinase that was originally identified as the key player in maintaining cellular energy homeostasis.

AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP / ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation.

AMPK is a highly conserved sensor of intracellular adenosine nucleotide levels that is activated when even modest decreases in ATP production result in relative increases in AMP or ADP. In response, AMPK promotes catabolic pathways to generate …

Oct 4, 2017 · AMP-activated protein kinase (AMPK) is a highly conserved sensor of low intracellular ATP levels that is rapidly activated after nearly all mitochondrial stresses, even those that do not...

Gene ID: 5562, updated on 9-Feb-2025. The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells.

The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that …