Aldehyde dehydrogenases (ALDH) (EC 1.2.1.3) are a family of nicotinamide adenine dinucleotide (phosphate) (NAD (P)) dependent enzymes, typically with a molecular mass of ca. 50–60 kDa. They oxidise a large range of aliphatic and aromatic, endogenous and exogenous aldehydes to form the corresponding carboxylic acids.

Aldehyde dehydrogenases (EC 1.2.1.3) are a group of enzymes that catalyse the oxidation of aldehydes. [2] . They convert aldehydes (R–C (=O) –H) to carboxylic acids (R–C (=O) –O–H). The oxygen comes from a water molecule. To date, nineteen ALDH genes have been identified within the human genome.

Aldehyde dehydrogenases (ALDHs) belong to a superfamily of enzymes that play a key role in the metabolism of aldehydes of both endogenous and exogenous derivation. The human ALDH superfamily comprises 19 isozymes that possess important …

Aldehyde dehydrogenase (ALDH) enzymes catalyze the NAD(P) +-dependent oxidation of a wide variety of endogenous and exogenous aldehydes to their corresponding acids. Some members of the ALDH superfamily of enzymes are abundantly expressed in the mammalian cornea and lens in a taxon-specific manner.

The aldehyde dehydrogenase (ALDH) gene superfamily encodes enzymes that are critical for certain life processes and detoxification via the NAD(P) +-dependent oxidation of numerous endogenous and exogenous aldehyde substrates, including …

Mar 1, 2013 · Aldehyde dehydrogenases (ALDHs) metabolize endogenous and exogenous aldehydes and thereby mitigate oxidative/electrophilic stress in prokaryotic and eukaryotic organisms. ALDHs are found throughout the evolutionary gamut, from single-celled organisms to complex multicellular species.

May 14, 2021 · ALDHs are responsible for the NAD (P)-dependent oxidation of aldehydes to carboxylic acids, participating in detoxification, biosynthesis, antioxidant and regulatory functions.

The aldehyde dehydrogenase (ALDH) 2 superfamily is a vast collection of enzymes that catalyze the NAD(P) +-dependent oxidation of aldehydes to carboxylic acids. Humans have 19 functional genes and three pseudogenes.

In enzymology, an aldehyde dehydrogenase (NAD+) (EC 1.2.1.3) is an enzyme that catalyzes the chemical reaction. The 3 substrates of this enzyme are aldehyde, NAD +, and H 2 O, whereas its 3 products are acid, NADH, and H +.

May 13, 2021 · ALDHs are responsible for the NAD (P)-dependent oxidation of aldehydes to carboxylic acids, participating in detoxification, biosynthesis, antioxidant and regulatory functions.