Immunolocalization of Cancer Stem Cells Marker ALDH1 and its ...
Nov 14, 2018 · Aldehyde dehydrogenase-1 (ALDH1) is associated with tumorigenesis, linked to treatment resistance and shown to identify cancer stem cells (CSC)-like cells. This study …
Aldehyde Dehydrogenase: An Off-Label Marker of Endothelial …
Jul 9, 2023 · In our study, we found (for the first time) a strong positivity of ALDH in OSCC tissues (mainly) and in the advanced stages of OL. Further studies in larger samples of patients with a …
ALDH1 as a prognostic marker for lymph node metastasis in OSCC
Oral squamous cell carcinoma (OSCC) has the second worst prognosis after laryngeal squamous cell carcinoma among HNCs; laryngeal squamous cell carcinoma has a progression-free 5 …
ALDH3A1 acts as a prognostic biomarker and inhibits the epithelial ...
Feb 19, 2020 · Results: In OSCC tissues, ALDH3A1 was significantly decreased compared to the adjacent normal tissues. Lower ALDH3A1 expression in OSCC tissues was associated with a …
ALDH and cancer stem cells: Pathways, challenges, and future …
Sep 1, 2024 · Aldehyde dehydrogenases are the cancer stem cells which plays a role in CSC progression. ALDH subunits can cause drug resistance. A systemic elucidation on the …
Inhibition of Bruton’s tyrosine kinase as a therapeutic strategy for ...
Ibrutinib reduced the number of aldehyde dehydrogenase (ALDH)-rich OSCC cells and reduced tumorsphere formation, migration, and invasion in a dose-dependent manner. Compared with …
DRP1 inhibition-mediated mitochondrial elongation abolishes …
Apr 6, 2024 · Our results converge with published findings to suggest suppression of DRP1 decreased the stemness of OSCC cells and the count of OSCC-CSCs with low intracellular …
The Antihelminthic Niclosamide Inhibits Cancer Stemness
Aug 24, 2018 · In the present study, we demonstrated that ALDH+ human oral squamous cell carcinoma (OSCC) cells are characterized by upregulated expression of the pluripotency …
Altered Presence of Cancer Stem Cell ALDH1/2 in Oral ... - PubMed
Jun 22, 2023 · The characteristic expression of ALDH in potentially malignant oral and OSCC lesions suggests the presence of CSCs and their possible implication in the early stages of …
Cancer Stem Cells in Oral Squamous Cell Carcinoma: A Narrative
Sep 16, 2024 · This narrative review summarizes the in vivo and in vitro evidence of CSCs and CSC-related signaling pathways in OSCC, highlighting their role in promoting …
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