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The Ark1/Prk1 family. The family of actin-regulating kinases in Saccharomyces cerevisiae comprises three members: Ark1, Prk1 and the lesser-studied Akl1.

100 years in the future, planetary colonization missions have begun as a necessity to help secure the survival of the human race. The first of these missions on a spacecraft known as Ark One encounters a catastrophic event causing massive destruction and loss of life.

Jun 22, 2021 · Receptor-like kinases (RLKs) are key cell signaling components. The rice ARBUSCULAR RECEPTOR-LIKE KINASE 1 (OsARK1) regulates the arbuscular mycorrhizal (AM) association postarbuscule development and belongs to an undefined subfamily of RLKs. Our phylogenetic analysis revealed that ARK1 has a …

Nov 2, 2020 · Here the authors show that ARK1, an armadillo repeat kinesin, interacts with the Arabidopsis atlastin RHD3 to guide ER tubule fusions via microtubules to generate a fine ER network.

Mar 1, 2003 · Ark1 was originally identified through a two‐hybrid screen for proteins that bind to Sla2 (Cope et al., 1999). The interaction is through the Ark1 C‐terminal region, which shows no homology with Prk1, indicating that the kinases may have distinct roles.

Aug 8, 2020 · Thus, ark1∆ prk1∆ are synthetically lethal with loss of YPK1 or ELM1, both of which are required for normal levels of TORC2 signaling. In addition, ark1∆ prk1∆ cells are exquisitely hypersensitive to myriocin, which inhibits production of sphingolipids that relay signals in the TORC2 network.

The Ark/Prk serine/threonine kinases initiate phosphorylation cycles that control the endocytic machinery in mammalian cells and in yeast, and the actin cytoskeleton in yeast. The members of this protein family are unified by homologies in their kinase domain, but are generally diverse in their other domains.

As a man or woman stranded, naked, freezing, and starving on the unforgiving shores of a mysterious island called ARK, use your skill and cunning to kill or tame and ride the plethora of leviathan dinosaurs and other primeval creatures roaming the land.

Gene ID: 855711, updated on 8-Feb-2025. Enables protein serine/threonine kinase activity. Involved in actin filament organization and regulation of clathrin-dependent endocytosis. Located in actin cortical patch. Orthologous to human BMP2K (BMP2 inducible kinase). [provided by Alliance of Genome Resources, Feb 2025]