Baicalin hydrate | C21H20O12 | CID 71311447 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

Baicalin hydrate exhibited a comparable effective Ki value of 26.98 ± 9.91 nM compared to Acarbose, which acts as a starch blocker, according to the results of the α-glycosidase inhibition.

Oct 29, 2023 · The structure of baicalin hydrate causes interference in the DPPH free radicals, according to the mechanism described between baicalin hydrate and DPPH . The DPPH radical scavenging activity was shown to increase with baicalin concentration.

In this review, we highlighted the signaling pathways of baicalin and baicalein in the treatment and chemoprevention anti-cancer, anti-inflammatory, antioxidative and cytoprotective properties as well as baicalin-baicalein’s interactions.

Baicalin hydrate; CAS Number: 206752-33-2; Synonyms: Baicalein 7-β-D-glucopyranosiduronate at Sigma-Aldrich

Jan 2, 2018 · We found that baicalin hydrate has a potential role in the maintenance of genome stability and alternative splicing. BH inhibited cell viability and tumor growth in NPC and induced early apoptosis and cell cycle arrest at the G2/M phase.

Oct 29, 2023 · Baicalin hydrate had an IC 50 value of 13.40 μg/mL (r 2: 0.9940) for DPPH radical scavenging, whereas BHA, BHT, Trolox, and α-Tocopherol had IC 50 values of 10.10, 25.95, 7.059, and 11.31 μg/mL for DPPH • scavenging, respectively.

Jan 2, 2018 · Our data indicate that the potentiating effect of baicalin hydrate is due to modulating the oxidative stress response, which in turn leads to increased tobramycin-mediated killing.

Dec 4, 2017 · Baicalin hydrate (BH), a natural compound, has been investigated for many years because of its traditional medicinal properties. However, the anti-tumor activities of BH and its epigenetic role in NPC have not been elucidated. In this study, we identified that BH inhibits NPC cell growth in vivo …

Oct 29, 2023 · The enzyme inhibition values of baicalin hydrate towards carbonic anhydrase isoenzyme II (CA II), acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and α-glycosidase (α-Gly).