Using a beta-glucuronidase (GUS) reporter-COP1 fusion transgene, it was shown previously that Arabidopsis COP1 acts within the nucleus as a repressor of seedling photomorphogenic development and that high inactivation of COP1 was accompanied by a reduction of COP1 nuclear abundance (A.G. von Arnim, X.-W. Deng [1994] Cell 79: 1035-1045).

The data suggest that multiple photoreceptors influence the light-regulated subcellular localization of COP1 in white light. Under specific wavelengths of light, phyA, phyB, and CRY1 each play critical roles in mediating far-red, red, and blue light signals, respectively.

Oct 1, 1998 · Our study reveals the distinct but overlapping functions of COP1 domains in the light control of seedling development, and provides a structural basis for COP1 as a molecular switch.

Mar 1, 1999 · The GUS–COP1 localization pattern suggests that COP1 acts in the nucleus to suppress photomorphogenic development in darkness, and the light-dependent inactivation of COP1 correlates with its reduced abundance in the nucleus.

Dec 16, 1994 · In Arabidopsis hypocotyl cells, the nuclear GUS-COP1 level changes in response to dark-light transitions and quantitatively correlates with the extent of repression of photomorphogenic development.

Dec 16, 1994 · In Arabidopsis hypocotyl cells, the nuclear GUS-COP1 level changes in response to dark-light transitions and quantitatively correlates with the extent of repression of photomorphogenic development.

Dec 25, 2001 · Through a semiquantitative analysis of the nuclear abundance of GUS-COP1 in the various genetic backgrounds, the specific roles of the individual photoreceptors have been established. The data suggest that multiple photoreceptors influence the light-regulated subcellular localization of COP1 in white light.

The Arabidopsis CONSTITUTIVE PHOTOMORPHOGENIC1 (COP1) protein plays a critical role in the repression of photomorphogenesis during Arabidopsis seedling development. We investigated the control of COP1 partitioning between nucleus and cytoplasm, ...

The β-glucuronidase- (GUS) COP1 fusion transgene used to demonstrate the light modulated subcellular localization of COP1 is fully functional in complementing a cop1 loss-of-function allele, cop1-5, suggesting that the modulation of subcellular localization is functionally significant (von Arnim et al., 1997).

Dec 16, 1994 · In Arabidopsis hypocotyl cells, the nuclear GUS-COP1 level changes in response to dark-light transitions and quantitatively correlates with the extent of repression of photomorphogenic development.