Oct 13, 2024 · The selection of the appropriate pore size of CPG is critical for achieving efficient separation and purification of molecules, and the use of CPG with a pore size that is too small or too large can result in poor separation efficiency and reduced yield.

Controlled pore glass (CPG) with pore sizes between 50 and 300 nm is also excellently suited for the synthesis of oligonucleotides. In this application, a linker, a nucleoside or a non-nucleosidic compound, is first attached to the surface of CPG.

Apr 15, 2021 · Controlled pore glass (CPG) is a high silica glass that includes pores with a particular size distribution. Porous glasses can be fabricated into a wide variety of geometric forms (such as beads, frit, plates, rods and hollow spheres), and pore sizes can be tuned precisely from the range of angstroms to millimeters.

LGC’s CPG solid supports are available in a variety of pore sizes and functionalised nucleoside loadings. Six pore sizes are offered from 500 Å to 3000 Å to enable the synthesis of oligonucleotides for nearly any application.

Oct 29, 2024 · The pore size of CPG can be controlled by varying the thermal treatment temperature, acid concentration, and leaching time. This allows for the production of CPG materials with a wide range of pore sizes, from a few nanometers to several hundred nanometers.

CUTAG CPG pore size 1000 Å, 25-35 μmol/g; Synonyms: CUTAG CPG; find Sigma-Aldrich-M403000 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich ... Essentially, there will be 25 to 35 micromoles of the functional group per gram of controlled pore glass (CPG). This is somewhat indicative of the yield ...

Controlled Pore Glass (CPG) has widely been used as the standard for solid-phase oligonucleotide synthesis, with features such as high surface area, uniform pore size and stability in synthesis solvents.

Oct 29, 2020 · Controlled pore glass (CPG) is a high-silica glass that contains pores with a specific size distribution. Porous glasses can be made into a wide range of geometric forms (such as frit, rods, plates, beads, and hollow spheres), and pore sizes can be precisely tuned from the range of angstroms to millimeters.

Dec 12, 2024 · Pore size: The pore size of CPG can be precisely controlled, ranging from a few nanometers to several micrometers. Surface area: CPG has a high surface area, which provides a large area for adsorption and reaction. Chemical inertness: CPG is resistant to corrosion and degradation, making it suitable for use in harsh environments.

Feb 9, 2022 · CPG is manufactured in a range of particle sizes, 40 to 200im, and different pore sizes, 7 to 300 nm (Table 3). The manufacturing batch sizes are generally much smaller than silica particles, possibly because of the heat treatment process.