
Caco-2 - Wikipedia
Caco-2 (from Cancer coli, "colon cancer") is an immortalized cell line of human colorectal adenocarcinoma cells. It is primarily used as a model of the intestinal epithelial barrier. [1] In …
Caco-2 [Caco2] - HTB-37 - ATCC
Caco-2 [Caco2] is an adherent cell line isolated from colon tissue derived from a patient with colorectal adenocarcinoma. These cells express characteristics of enterocytic differentiation …
Caco-2 Cell Line - PubMed
The human epithelial cell line Caco-2 has been widely used as a model of the intestinal epithelial barrier. The Caco-2 cell line is originally derived from a colon carcinoma.
Caco-2 Cell Line Standardization with Pharmaceutical …
In this review, we presented permeability tests in the Caco-2 model used for both scientific (e.g., drug absorption prediction) and regulatory purposes (e.g., formal classification of substances …
Evaluation of Caco-2 and human intestinal epithelial cells as
Although the colonic cell line Caco-2 is widely used as a model of the small intestinal barrier function, it has limitations such as overestimated transepithelial electrical resistance (TEER) …
Caco-2 - an overview | ScienceDirect Topics
Caco-2, a cell line obtained from human colon adenocarcinoma, is the most well-established intestinal cell model to date. Caco-2 cells differentiate into enterocyte-like cells after 21 days in …
Unraveling Caco-2 cells through functional and transcriptomic ...
Feb 1, 2025 · In this study, we investigated functional and morphological aspects of Caco-2 cells, alongside their transcriptomic profiles, with a particular emphasis on genes encoding drug …
Caco-2 Cell Line - An Extensive Guide to CaCo-2 cells in ... - Cytion
The Caco-2 cell line is instrumental in understanding the function and molecular details of intestinal epithelium efflux systems, such as P-glycoprotein, crucial for drug development.
Caco-2 Permeability: Key Factors in Drug Transport
6 days ago · The Caco-2 cell model, derived from human colon carcinoma cells, mimics the intestinal barrier in drug permeability studies. By forming a monolayer with characteristics …
Caco-2 Cell Line - SpringerLink
The human epithelial cell line Caco-2 has been widely used as a model of the intestinal epithelial barrier. The Caco-2 cell line is originally derived from a colon carcinoma. However, one of its …