Caco-2 (from Cancer coli, "colon cancer") is an immortalized cell line of human colorectal adenocarcinoma cells. It is primarily used as a model of the intestinal epithelial barrier. [1] In …

Caco-2 [Caco2] is an adherent cell line isolated from colon tissue derived from a patient with colorectal adenocarcinoma. These cells express characteristics of enterocytic differentiation …

The human epithelial cell line Caco-2 has been widely used as a model of the intestinal epithelial barrier. The Caco-2 cell line is originally derived from a colon carcinoma.

In this review, we presented permeability tests in the Caco-2 model used for both scientific (e.g., drug absorption prediction) and regulatory purposes (e.g., formal classification of substances …

Although the colonic cell line Caco-2 is widely used as a model of the small intestinal barrier function, it has limitations such as overestimated transepithelial electrical resistance (TEER) …

Caco-2, a cell line obtained from human colon adenocarcinoma, is the most well-established intestinal cell model to date. Caco-2 cells differentiate into enterocyte-like cells after 21 days in …

Feb 1, 2025 · In this study, we investigated functional and morphological aspects of Caco-2 cells, alongside their transcriptomic profiles, with a particular emphasis on genes encoding drug …

The Caco-2 cell line is instrumental in understanding the function and molecular details of intestinal epithelium efflux systems, such as P-glycoprotein, crucial for drug development.

6 days ago · The Caco-2 cell model, derived from human colon carcinoma cells, mimics the intestinal barrier in drug permeability studies. By forming a monolayer with characteristics …

The human epithelial cell line Caco-2 has been widely used as a model of the intestinal epithelial barrier. The Caco-2 cell line is originally derived from a colon carcinoma. However, one of its …