Oct 15, 2024 · Here, we engineered a nanoplatform based on CaO 2 nanoparticles (NPs) capable of encapsulating curcumin (CUR) and self-supplying H 2 O 2 for synergistic CDT-augmented antitumor immunotherapy (CaO 2 @CUR@ZIF-Cu, denoted as CCZC).

Nov 5, 2024 · Upon reaching the acidic TME, the ZIF-8 shell decomposed to release CaO 2, which generated O 2 in situ to relieve tumor hypoxia and enhance the PDT efficacy of ICG under near-infrared irradiation.

Calcium peroxide (CaO2) is a stable hydrogen peroxide (H2O2) carrier, and the CaO2/Fe(II) system has been applied for treatment of various pollutants. It is commonly reported in the literature that hydroxyl radical (HO ) and superoxide radical ...

Jan 25, 2024 · Calcium peroxide (CaO 2) has recently attracted much attention as an oxygen-releasing biomaterial for tissue engineering. CaO 2 has also been used in cancer therapies, such as photodynamic therapy. However, the uncontrollability of oxygen release after immersion in water is a challenge.

Here, we engineered a nanoplatform based on CaO 2 nanoparticles (NPs) capable of encapsulating curcumin (CUR) and self-supplying H 2 O 2 for synergistic CDT-augmented antitumor immunotherapy (CaO 2 @CUR@ZIF-Cu, denoted as CCZC).

Herein, a cascade nanoreactor CaCuZC has been constructed by incorporating nanosonosensitizer IR780 carbon dots (IR780 CD) and calcium peroxide (CaO 2) into metal-organic frameworks (MOF) for synergistic cuproptosis-ferroptosis and Ca 2+ overload mediated immunotherapy.

Sep 12, 2023 · CaO 2 nanoparticles have been explored for cancer treatment through three main mechanisms: (1) the release of O 2, which helps alleviate tumor hypoxia and enhances oxygen-dependent therapies such as chemotherapy, photodynamic therapy, and immunotherapy; (2) the generation of H 2 O 2, a precursor for ·OH generation, which enables cancer chemodyna...

Sep 12, 2023 · CaO 2 nanoparticles have been explored for cancer treatment through three main mechanisms: (1) the release of O 2, which helps alleviate tumor hypoxia and enhances oxygen-dependent therapies such as chemotherapy, photodynamic therapy, and immunotherapy; (2) the generation of H 2 O 2, a precursor for ·OH generation, which enables cancer chemodyna...

Sep 30, 2024 · The in vitro antimicrobial experiments demonstrated that CaO 2 /POM@MOF possessed the combined CDT and PTT effect and exhibited excellent antimicrobial efficacy. …

At present, there are three main methods to prepare CaO 2 at home and abroad: CaCl 2 method, CaO method, and Ca (OH) 2 method. Ca (OH) 2 method is divided into traditional method, spray drying method, and air cathode method.

Jul 1, 2024 · Comprehensive Overview: Explores synthesis, functionalization, and applications of CaO 2 NPs, with recent advancements. Mechanistic Insights: Unveils antibacterial mechanisms, emphasizing ROS generation and biofilm disruption. Diverse Applications: Evaluates broad spectrum efficacy and applications as antibacterial agents.

Nov 4, 2024 · In this study, platelet membrane-camouflaged copper-doped CaO 2 biomimetic nanomedicines have been developed for breast cancer treatments.

Dec 19, 2017 · Calcium peroxide from alkaline earth metal peroxide groups has been proposed as an appropriate compound for supplying sufficient oxygen to cells within the scaffolds. The high surface-to-volume ratio of CaO 2 particles can lead to an increase in oxygen generation ability over a particular time interval.

Aug 21, 2023 · CaO 2 serves as a 'drug' precursor, steadily and continuously releasing calcium ions (Ca 2+) and hydrogen peroxide (H 2 O 2) under mildly acidic conditions, while PAA-CaO 2 nanoparticles exhibited good spray behavior in aqueous form.

Jun 1, 2023 · In this work, innovative biochar-loaded CaO 2 was prepared by an in-situ precipitation method. The biochars were modified using base-/acid-treatment to establish the relationship between the biochar properties and the oxygen releasing performance.

We report that incorporating nanosized calcium peroxide (nCaO2) and manganese oxide nanosheets (nMnO2) into hydrophobic polymeric microparticles enables precise modulation of oxygen release...

Calcium peroxide | CaO2 | CID 14779 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

Arterial oxygen content (CaO2) represents the total amount of oxygen carried in arterial blood, expressed in milliliters of oxygen per deciliter of blood (mL O2/dL). It's a crucial parameter for assessing oxygen delivery to tissues and is particularly important in critical care settings.

Calcium peroxide or calcium dioxide is the inorganic compound with the formula CaO 2. It is the peroxide (O 22−) salt of Ca 2+. Commercial samples can be yellowish, but the pure compound is white. It is almost insoluble in water. [3] As a solid, it is relatively stable against decomposition.

Dec 25, 2024 · Activation of the Cu (I)/Cu (II) cycle by exogenously generated H 2 O 2 from the CaO 2 nanoshell significantly enhanced glutathione (GSH) depletion. CuO@CaO 2 NSs exhibited a 2-fold higher GSH depletion rate compared to pristine CuO NSs.