CD27 - Wikipedia
CD27 is a member of the tumor necrosis factor receptor superfamily. [5] It is currently of interest to immunologists as a co-stimulatory immune checkpoint molecule, and is the target of an anti …
CD27 Gene - GeneCards | CD27 Protein | CD27 Antibody
Dec 24, 2024 · CD27 (CD27 Molecule) is a Protein Coding gene. Diseases associated with CD27 include Lymphoproliferative Syndrome 2 and Combined T Cell And B Cell Immunodeficiency. …
CD27 is required for generation and long-term maintenance of T …
The Traf-linked tumor necrosis factor receptor family member CD27 is known as a T cell costimulatory molecule.
CD27 - an overview | ScienceDirect Topics
CD27 is a costimulatory molecule associated with CD27 Deficiency, a condition characterized by immunodeficiency, EBV lymphoproliferative disease, reduced T cell proliferation, and …
CD27: marker and mediator of T-cell activation? - PubMed
CD27 is a lymphocyte-specific member of the tumour necrosis factor receptor (TNF-R) family, expression of which is tightly regulated during T-cell ontogeny. Recently, the ligand for CD27 …
New emerging targets in cancer immunotherapy: CD27 (TNFRSF7)
The CD27 agonistic antibody varlilumab showed promising efficacy in haematological as well as solid cancers. Current studies investigate the combination of the CD27 agonistic antibody …
CD27− CD4+ memory T cells define a differentiated memory population …
The CD27 − memory population was the only cell population that displayed a clear-cut recall response to all four antigens . The CD27 + memory population showed a recall response as …
New emerging targets in cancer immunotherapy: CD27 (TNFRSF7)
Cluster of differentiation 27 (CD27) is a member of the tumour necrosis factor receptor superfamily and plays a key role in T-cell activation by providing a costimulatory signal. Bound …
CD27 is a thymic determinant of the balance between interferon
Mar 8, 2009 · Here we show that most γδ T lymphocytes expressed the tumor necrosis factor receptor family member CD27 and secreted interferon-γ, whereas interleukin 17 production …
CD27 - CD27 antigen - Homo sapiens (Human) | UniProtKB | UniProt
Nov 24, 2009 · The CD70-CD27 signaling pathway mediates antigen-specific T-cell activation and expansion which in turn provides immune surveillance of B-cells (PubMed:28011863).