Desmosome is a intercellular junction in animal cell. A desmosome (/ ˈdɛzməˌsoʊm /; [1][2] "binding body"), also known as a macula adherens (plural: maculae adherentes) (Latin for adhering spot), is a cell structure specialized for cell-to- cell adhesion.

Apr 27, 2017 · Desmosomes are a type of anchoring junction in animal tissues that connect adjacent cells. Anchoring junctions are button-like spots found all around cells that bind adjacent cells together.

Desmosomes are specialized and highly ordered membrane domains that mediate cell-cell contact and strong adhesion. Adhesive interactions at the desmosome are coupled to the intermediate filament cytoskeleton.

The desmosome is a cell–cell adhesive junction that provides integrity and mechanical resistance to tissues through its attachment to the intermediate filament cytoskeleton. Defects in desmosomes cause diseases impacting the heart, epidermis, and other epithelia.

Jul 26, 2011 · Desmosomes are specialized adhesive protein complexes that localize to intercellular junctions and are responsible for maintaining the mechanical integrity of tissues. The term ‘desmosome’ was coined by Josef Schaffer in 1920 and has its origins in the Greek words for bond (desmo) and body (soma).

Desmosomes are one of four intercellular junctions present on the lateral side of neighboring polarized epithelial cells. Tight junctions and adherens junctions (AJs) are restricted to the apical domain, where they form the epithelial barrier and organize cortical actin, respectively.

Mar 4, 2024 · Desmosomes are cell junctions that provide strong adhesive connections between cells. They help cells stick together. Desmosomes play a crucial role in maintaining tissue integrity and strength by connecting adjacent cells through specialized proteins called cadherins.

Aug 19, 2022 · A desmosome, also known as a macula adherens, is one of animal cells’ anchoring junctions. They are cell-cell, intercellular junctions that connect adjacent cells in tissues that experience stress. Giulio Bizzozero, an Italian pathologist, first discovered it. Josef Schaffer coined the term ‘desmosome’ in 1920. Location of Desmosomes in a ...

Mar 1, 2008 · Desmosomes are intercellular junctions that provide strong adhesion between cells. Because they also link intracellularly to the intermediate filament cytoskeleton they form the adhesive bonds in a network that gives mechanical strength to tissues.

Jun 24, 2021 · A desmosome aids in cell-to-cell adhesion. It attaches the cell to its neighboring cell. One of a number of differentiated regions which occur, for example, where the cytoplasmic membranes of adjacent epithelial cells are closely apposed.