Enterolactone is an organic compound classified as an enterolignan. It is formed by the action of intestinal bacteria on plant lignan precursors present in the diet.

Enterolactone, the most abundant mammalian lignan, is a moderate inhibitor of placental aromatase and competes with the natural substrate androstenedione for the enzyme. Other experiments with a choriocarcinoma cell line (JEG-3) showed that enterolactone is very readily transferred from cell culture media into the cells [32]. Most of the ...

Recently, phytoestrogens, such as lignans with estrogen-like biological activities, have attracted attention for their potential effects in the prevention or treatment of estrogen-related diseases. Enterodiol (END) and enterolactone (ENL) are mammalian lignans, which can reduce the risk of various cancers.

Enterolactone (EL) is a bioactive phenolic metabolite known as a mammalian lignan derived from dietary lignans. Here in we review the reported anti-cancer properties of EL at preclinical as well as clinical level.

A significant amount of substantiation from epidemiological, clinical and laboratory research highlights the importance of diet and nutrition in cancer chemoprevention. Enterolactone (EL) is a bioactive phenolic metabolite known as a mammalian lignan derived from dietary lignans.

Lignans are plant compounds metabolized in the mammalian gut to produce the estrogenic enterolignans, enterodiol (ED) and enterolactone (EL). Because estrogens have been linked to breast cancer etiology, enterolignans could affect breast cancer risk, but to our knowledge, the mechanisms by which the …

Jun 5, 2019 · Enterolactone (EL) is a bioactive phenolic metabolite known as a mammalian lignan derived from dietary lignans. Here in we review the reported anti-cancer properties of EL at preclinical as well as clinical level.

Enterolactone is a compound produced by colonic microflora from plant lignans and their glucosides. It exhibits weakly estrogenic and antiestrogenic activities, and has been associated with protective effects against certain types of cancers, such as …

Enterolactone | C18H18O4 | CID 114739 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.

have attracted much attention. Many reviews have been written on enterolactone, however, the majority of these focused on the properties of enterolactone with few on its synthesis. Here, we outline both the medicinal properties of enterolactone and the various ways in which it has been synthesized. 2. Biology Overview 2.1.