The electroretinogram (ERG) is a sensitive and noninvasive method for testing retinal function. In this protocol, we describe a method for performing ERGs in mice. Contact lenses on the mouse cornea measure the electrical response to a light ...

The ERG is a sensitive measure of changes in retinal function that are pan-retinal, but ... The ERG is the sum of all retinal activity. The ERG is usually recorded from the cornea, which acts as an antenna that collects and sums signals from the retina.

The repeatability of Celeris Light Guide Electrodes (LGE) was demonstrated on mice by positioning the LGE’s in 3 positions (perpendicular to eye, maximum angle rotated up on eye, maximum angle rotated down on eye) and then recording ERG’s in each case.

This study investigated contributions from the retinal On and Off pathways, and the spiking and nonspiking activity of neurons in those pathways to the pattern ERG of the mouse. Light-adapted pattern and ganzfeld ERGs were recorded from anesthetized ...

Sep 25, 2020 · Light adaptation changes both the sensitivity and maximum amplitude (R max) of the mouse photopic electroretinogram (ERG) b-wave. Using the ERG, we examined how modulation of gap junctional coupling between rod and cones alters the light-adapted ERG.

Purpose: The electroretinogram (ERG) is an appropriate method to evaluate the retinal function in a variety of animal models. In this study we present suitable conditions of stimulation and recording in the dark-adapted mouse.

In scotopic ERGs, mice are presented with low intensity light flashes to induce rod activation, so the function photoreceptor and downstream retinal cells can be of rod examined ( Fu, 2010).

ERGs were recorded in live mice of both sexes as described previously (15, 38) using the Espion E2 system with a ColorDome Ganzfeld stimulator (Diagnosys LLC, Littleton, MA). Briefly, after...

Purpose: To describe and evaluate a novel method to determine the validity of measurements made using cycle-by-cycle (CxC) recording techniques in patients with advanced retinal degenerations (RD) having low-amplitude flicker electroretinogram (ERG) responses.

C3HeB/FeJ mice as well as in 129/SvJ blind mice with lowered ERG response were shown to be homozygous Pde6b rd1 carriers. Some presumably heterozygous carriers were identified among the 129/SvJ mice with normal ERG.